GS1 Application Identifiers (AIs) are prefixes used in 2D codes to define the meaning and format of the data elements that follow. In pharmaceutical serialization, AIs ensure that each piece of information in a GS1 DataMatrix 2D code is correctly interpreted by scanning systems.
AIs provide a standardized way to encode different types of information in a single 2D code, enabling global interoperability and ensuring that pharmaceutical products can be properly identified and tracked throughout the supply chain.
AIs are enclosed in parentheses and precede the actual data. For example, "(01)01234567890123" where "01" is the AI and "01234567890123" is the GTIN data.
Each AI defines the format, length, and validation rules for the following data, ensuring consistent interpretation across different systems and countries.
Multiple AIs can be concatenated in a single 2D code, allowing multiple pieces of information to be encoded together. The 2D code scanner automatically separates and interprets each AI and its associated data.
Essential AIs used in GS1 DataMatrix barcodes for pharmaceutical products
Identifies the specific product and its packaging configuration
Identifies the production batch or lot
Indicates when the product expires (YYMMDD format)
Unique identifier for each individual package
Country-specific code for healthcare reimbursement
Decoded Information:
Decoded Information:
All AIs used in pharmaceutical serialization must comply with GS1 General Specifications, ensuring global interoperability and consistent data interpretation.
Certain AIs (like GTIN) include check digits for data integrity verification. The check digit is calculated using the GS1 standard algorithm and helps detect scanning errors.
Each AI has specific format requirements (numeric, alphanumeric, length limits) that must be validated to ensure proper 2D code generation and scanning.
Important: GS1 DataMatrix codes require specialized encoding software and cannot be handled the same way as regular DataMatrix codes. Scanners can clearly identify improperly encoded codes and will reject them.
GTIN-14 structure: Company Prefix (7-12 digits) + Item Reference (1-6 digits) + Check Digit (1 digit). The GTIN prefix identifies the GS1 member organization that assigned the number.
GTIN (01), Serial Number (21), Batch Number (10), and Expiry Date (17) are mandatory for EU serialization. NHRN (71x) is optional and depends on national requirements.
While AIs can be in any order, it's recommended to follow a logical sequence for better readability and system compatibility.
Including more AIs increases 2D code size. Consider packaging constraints and scanning requirements when deciding which AIs to include.
Information may be outdated. Always consult official documentation from EMVO, EMA, GS1, and national regulatory bodies for current requirements.